Wondering what's going on in our brains? Check out some recommended open access publications and our personal meta-analysis to give you the rundown on the medical and scientific side of stuttering.
Currently, Rishit is working on a comprehensive meta-analysis that examines the efficacy of behavioral, neuromodulatory, and assistive interventions for stuttering. Drawing from randomized controlled trials and crossover studies, the project evaluates outcomes such as percent syllables stuttered, Stuttering Severity Instrument (SSI-4) scores, and the Overall Assessment of the Speaker’s Experience of Stuttering (OASES). By separating short-term improvements (immediate to six weeks) from longer-term durability, the analysis highlights which therapies show sustained benefits and where gains tend to fade. Participants of the StutterSense Research Group are welcome to participate in this initiative!
Note: The uploaded slideshow is a draft in progress. Research is an ongoing process with consistent refinement, so changes and follow-ups will be made accordingly!
Recommended Publications:
A recent study found that people who stutter have higher iron levels in key speech-related brain areas — like the putamen and motor speech cortex.
Using quantitative MRI (specifically, quantitative susceptibility mapping), researchers showed that these elevated iron levels might relate to dopamine activity or other neural processes tied to speech control.
A recent study explored how transcranial direct current stimulation (tDCS)—a non-invasive brain stimulation technique—can improve speech fluency in adults who stutter. By applying tDCS over the left inferior frontal cortex, researchers observed notable enhancements in speech flow. This suggests that targeting specific brain regions with tDCS could be a promising approach for stuttering therapy.
This study looked at the DNA of over 1,800 people who stutter and found new genetic variants associated with neuronal development and dopamine signaling. Using genome-wide association studies (GWAS), researchers identified changes on chromosome 3 that may play a role in persistent developmental stuttering.
It's one of the largest genetic studies on stuttering so far — and it helps connect the dots between speech and brain biology.
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